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Phalanx Biotech human onearray v7.1 microarray
Effects of LXX-8250 on PFKFB4 expression. (A) Heatmap for the representative downregulated genes in LXX-8250 (14.6 μM) treated cells compared with control cells, as evaluated by <t>microarray</t> analyses (fold change>1.5, p < 0.05). (B) The relative PFKFB4 mRNA expression levels in SKCM data from TCGA combined with Skin data from GTEx data. Tumor, 469 cases; Normal, 557 cases. (C,D) Real time PCR analyses for the cells treated with LXX-8250 14.6 μM, (C) ; 22.8 µΜ, (D) . (E,F) Western blot analysis for the cells treated with LXX-8250 14.6 μM, (E) ; 22.8 µΜ, (F) for the indicated times. The quantification results of the band density were labeled above the bands. Data represent mean ± SD. ** p < 0.01, *** p < 0.001.
Human Onearray V7.1 Microarray, supplied by Phalanx Biotech, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/human onearray v7.1 microarray/product/Phalanx Biotech
Average 90 stars, based on 1 article reviews
human onearray v7.1 microarray - by Bioz Stars, 2026-05
90/100 stars

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1) Product Images from "β-elemene Isopropanolamine Derivative LXX-8250 Induces Apoptosis Through Impairing Autophagic Flux via PFKFB4 Repression in Melanoma Cells"

Article Title: β-elemene Isopropanolamine Derivative LXX-8250 Induces Apoptosis Through Impairing Autophagic Flux via PFKFB4 Repression in Melanoma Cells

Journal: Frontiers in Pharmacology

doi: 10.3389/fphar.2022.900973

Effects of LXX-8250 on PFKFB4 expression. (A) Heatmap for the representative downregulated genes in LXX-8250 (14.6 μM) treated cells compared with control cells, as evaluated by microarray analyses (fold change>1.5, p < 0.05). (B) The relative PFKFB4 mRNA expression levels in SKCM data from TCGA combined with Skin data from GTEx data. Tumor, 469 cases; Normal, 557 cases. (C,D) Real time PCR analyses for the cells treated with LXX-8250 14.6 μM, (C) ; 22.8 µΜ, (D) . (E,F) Western blot analysis for the cells treated with LXX-8250 14.6 μM, (E) ; 22.8 µΜ, (F) for the indicated times. The quantification results of the band density were labeled above the bands. Data represent mean ± SD. ** p < 0.01, *** p < 0.001.
Figure Legend Snippet: Effects of LXX-8250 on PFKFB4 expression. (A) Heatmap for the representative downregulated genes in LXX-8250 (14.6 μM) treated cells compared with control cells, as evaluated by microarray analyses (fold change>1.5, p < 0.05). (B) The relative PFKFB4 mRNA expression levels in SKCM data from TCGA combined with Skin data from GTEx data. Tumor, 469 cases; Normal, 557 cases. (C,D) Real time PCR analyses for the cells treated with LXX-8250 14.6 μM, (C) ; 22.8 µΜ, (D) . (E,F) Western blot analysis for the cells treated with LXX-8250 14.6 μM, (E) ; 22.8 µΜ, (F) for the indicated times. The quantification results of the band density were labeled above the bands. Data represent mean ± SD. ** p < 0.01, *** p < 0.001.

Techniques Used: Expressing, Control, Microarray, Real-time Polymerase Chain Reaction, Western Blot, Labeling



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Phalanx Biotech human onearray v7.1 microarray
Effects of LXX-8250 on PFKFB4 expression. (A) Heatmap for the representative downregulated genes in LXX-8250 (14.6 μM) treated cells compared with control cells, as evaluated by <t>microarray</t> analyses (fold change>1.5, p < 0.05). (B) The relative PFKFB4 mRNA expression levels in SKCM data from TCGA combined with Skin data from GTEx data. Tumor, 469 cases; Normal, 557 cases. (C,D) Real time PCR analyses for the cells treated with LXX-8250 14.6 μM, (C) ; 22.8 µΜ, (D) . (E,F) Western blot analysis for the cells treated with LXX-8250 14.6 μM, (E) ; 22.8 µΜ, (F) for the indicated times. The quantification results of the band density were labeled above the bands. Data represent mean ± SD. ** p < 0.01, *** p < 0.001.
Human Onearray V7.1 Microarray, supplied by Phalanx Biotech, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/human onearray v7.1 microarray/product/Phalanx Biotech
Average 90 stars, based on 1 article reviews
human onearray v7.1 microarray - by Bioz Stars, 2026-05
90/100 stars
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Effects of LXX-8250 on PFKFB4 expression. (A) Heatmap for the representative downregulated genes in LXX-8250 (14.6 μM) treated cells compared with control cells, as evaluated by microarray analyses (fold change>1.5, p < 0.05). (B) The relative PFKFB4 mRNA expression levels in SKCM data from TCGA combined with Skin data from GTEx data. Tumor, 469 cases; Normal, 557 cases. (C,D) Real time PCR analyses for the cells treated with LXX-8250 14.6 μM, (C) ; 22.8 µΜ, (D) . (E,F) Western blot analysis for the cells treated with LXX-8250 14.6 μM, (E) ; 22.8 µΜ, (F) for the indicated times. The quantification results of the band density were labeled above the bands. Data represent mean ± SD. ** p < 0.01, *** p < 0.001.

Journal: Frontiers in Pharmacology

Article Title: β-elemene Isopropanolamine Derivative LXX-8250 Induces Apoptosis Through Impairing Autophagic Flux via PFKFB4 Repression in Melanoma Cells

doi: 10.3389/fphar.2022.900973

Figure Lengend Snippet: Effects of LXX-8250 on PFKFB4 expression. (A) Heatmap for the representative downregulated genes in LXX-8250 (14.6 μM) treated cells compared with control cells, as evaluated by microarray analyses (fold change>1.5, p < 0.05). (B) The relative PFKFB4 mRNA expression levels in SKCM data from TCGA combined with Skin data from GTEx data. Tumor, 469 cases; Normal, 557 cases. (C,D) Real time PCR analyses for the cells treated with LXX-8250 14.6 μM, (C) ; 22.8 µΜ, (D) . (E,F) Western blot analysis for the cells treated with LXX-8250 14.6 μM, (E) ; 22.8 µΜ, (F) for the indicated times. The quantification results of the band density were labeled above the bands. Data represent mean ± SD. ** p < 0.01, *** p < 0.001.

Article Snippet: Gene microarray analyses were performed by Phalanx Biotech Group using the Human OneArray ® V7.1 microarray.

Techniques: Expressing, Control, Microarray, Real-time Polymerase Chain Reaction, Western Blot, Labeling